Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGHVENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGR----YIVICYKATEFSG-TLQSSEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF 3FK9 Chain:A ((7-115)) ------------CIVVDHDQ---VLLLQKPRRGWWVA---PGGKMEAGESILETVKREYWEETGITVKNPELKGIFSMVIFDEGKIVSEWMLFTFKATEHEGEMLKQSPEGKLEWKKKDEVLELPMA---------------------------------

General information: TITO was launched using: RESULT: Template: 3FK9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 391 -9831 -25.14 -94.53 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -25.14 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.460

(partial model without unconserved sides chains): PDB file : Tito_3FK9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FK9-query.scw PDB file : Tito_Scwrl_3FK9.pdb: