Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDASDFLEA-DIAIVATYTYGDG--ELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAVDDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG 5V56 Chain:A ((382-507)) -AKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYFCGAVDAIEEKLKNLGAEIVQDGLRID-----------------------

General information: TITO was launched using: RESULT: Template: 5V56.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 637 -19991 -31.38 -162.53 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -31.38 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.572

(partial model without unconserved sides chains): PDB file : Tito_5V56.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5V56-query.scw PDB file : Tito_Scwrl_5V56.pdb: