Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDIEALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTALNRLNLKIKLYKEGKF 5D8C Chain:A ((10-120)) -----AAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAK-

General information: TITO was launched using: RESULT: Template: 5D8C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 239 -35836 -149.94 -322.85 target 2D structure prediction score : 0.77 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -149.94 2D Compatibility (Sec. Struct. Predict.) : 0.77 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.685

(partial model without unconserved sides chains): PDB file : Tito_5D8C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D8C-query.scw PDB file : Tito_Scwrl_5D8C.pdb: