Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLVLGGLSAAIMAVSGSVMAADFVAGKDYTVIANPGKVEVPGKIEVREFFWYGCLHCFKLEPHMQTWLKQIPSDVRFVRTPAAMNKVWEQGARTYYTSEALGVRKRTHLPLFHAIQVNGQQIFDQASAAKFFTRYGVPEQKFNSTYNSFAVTAKVAESNKLAQQYQLTGVPAVVVNGKYVVQ-GEDGKVTQVL---NYLIEKERKAK 5TLQ Chain:A ((3-187)) -----------------------DYTAGKEYVELSSPVPVSQPGKIEVVELFWYGCPHCYAFEPTIVPWSEKLPADVHFVRLPALFGGIWNVHGQMFLTLESMGVEHDVHNAVFEAIHKEHKKLATPEEMADFLAGKGVDKEKFLSTYNSFAIKGQMEKAKKLAMAYQVTGVPTMVVNGKYRFDIGSAGGPEETLKLADYLIEKERAA-

General information: TITO was launched using: RESULT: Template: 5TLQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 763 -79220 -103.83 -437.68 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -103.83 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_5TLQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5TLQ-query.scw PDB file : Tito_Scwrl_5TLQ.pdb: