Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPLLQIAEPGQSSAPHQHRIAIGIDLGTTHSLAATVLSGKPKVLNDVQNRRLLPSIVHYGDNTTHYGEEAKPFIIADPKNTIVSVKRFMGRSKADIKFQHPYELVGSEKNEMPAFETRAGRKTPVEISAEILKQLKDRAEDSLQNPVNGAVITVPAYFDEAQRQATRYAAQLAGLNILRLLNEPTAAAVAYGLDQESNLATDRNYVIYDLGGGTFDVSILRFSQGVFEVLATGGHTALGGDDLDRLIVKWA----KKQLNIDVLSDEDYAV--FIVAARQAKEQLS--TQDSVELKLLEAT--------LTLDRPTFESIIQVALDKTISVCKRVLRDAKLELTDIQNVVLVGGSTRSYAVQKAVREVFAQEPLCTINPDEVVAIGASITANQLIGNSQDGSLLLDVTPLSLGLETMGGLVERLISRNTAIPVARRQEFTTYQDGQTAMLIHVVQGERDLVEHCRSLGRFVLHGIPPMTAGQARIEVTFQVDADGLLTVSAREATSGVQAHIDIKPSYGLSEADTERLLIEGFQHAEEDKNLRHLKETKVEAERELEALEQALKVDADLLDEKQLEALNSAKESLKAQLEGSDIQAIEQAVQQLKVHSDAFAALRMNRHIDHALKGTKLDDWSKSN 2V7Y Chain:A ((5-504)) ---------------------IGIDLGTTNSCVAVLEGGEVKVIPNPEGNRTTPSVVAFKNGERLVGEVAKRQAITNP-NTIISIKRHMG---TDYKV-----------------EIEGKQYTPQEISAIILQYLKSYAEDYLGEPVTRAVITVPAYFNDAQRQATKDAGRIAGLEVERIINEPTAAALAYGLDKEE----DQTILVYDLGGGTFDVSILELGDGVFEVKATAGDNHLGGDDFDQVIIDYLVNQFKQEHGID-LSKDKMALQRLKDAAEKAKKELSGVTQTQISLPFISANENGPLHLEMTLTRAKFEELSAHLVERTMGPVRQALQDAGLTPADIDKVILVGGSTRIPAVQEAIKRELGKEPHKGVNPDEVVAIGAAIQGGVIAGEVKD-VVLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFTTAADNQTTVDIHVLQGERPMAADNKSLGRFQLTGIPPAPRGVPQIEVTFDIDANGIVHVRAKDLGTNKEQSITIKSSSGLSEEEIQRMIKEAEENAEADRKRKEAAEL----------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2V7Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2561 -21837 -8.53 -45.12 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -8.53 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.542

(partial model without unconserved sides chains): PDB file : Tito_2V7Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V7Y-query.scw PDB file : Tito_Scwrl_2V7Y.pdb: