Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNI-EIRTDKNIHNSERLITYVRAELTQEFQRHSERITHFSVHFSDENGDKGGDKDIHCMIEARPSGLKPVAVHHKAGNIDASIHGAIEKLKRSLEHTFEKKEHPRGGQPEFIDDEV 2YWQ Chain:A ((1-95)) MNIYKLIG-RNLEITDAIRDYVEKKLA-RLDRYQDGELMAKVVLSLAG-------KARAEIQVDLPG-GLVRVEEEDADLYAAIDRAVDRLETQVKRFR------------------

General information: TITO was launched using: RESULT: Template: 2YWQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 384 -49404 -128.65 -567.86 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -128.65 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.74 QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_2YWQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YWQ-query.scw PDB file : Tito_Scwrl_2YWQ.pdb: