Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSTILVIHGPNLNLLGKREPEVYGHLTLDNINQQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQPSNPN 4RHC Chain:A ((2-151)) -SSTILVIHGPNLNLLGKREPEVYGHLTLDNINRQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQPSNPN

General information: TITO was launched using: RESULT: Template: 4RHC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 730 -128348 -175.82 -855.65 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.99 3D Compatibility (PKB) : -175.82 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.99 QMean score : 0.605

(partial model without unconserved sides chains): PDB file : Tito_4RHC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RHC-query.scw PDB file : Tito_Scwrl_4RHC.pdb: