Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLQAVYLTPIELHQTPDWSDRPYNIHRDPLWKTEKQGKEFDDVWFYHCDHLGTPQEMTDHTGAIIWKAEYKAWGECKAEKAKSNFFENSEIISNNIRFQGQYFDEETGLHYNRYRYYSPYVGRFVSKDPIGLLGGSNNYAYAPSPTEWVDPLGLSCQKIPKGFKSFGQLKQFGQAMQAGFSKLGFKGA-TMYMQGSAHSGRSFETGKAFDDGRVSDFDIAVVQPELFEKAKKMGIAKGNRTLPIEINSVEANKLGINGVLQKMSKLAGGRDVNVMIFDSPESAKAKAEGTRIPANCM 1DLI Chain:A ((236-352)) -------------------------------------------------------------------------------------------------IQGISYDDRIGMHYNNPSF--GYGGYCLPKDTKQLLANYNNI-----PQTLIEAI-VSSNNVRKSYIA----KQIINVLKEQESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEPML-----------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1DLI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 331 -1254 -3.79 -10.81 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -3.79 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.081

(partial model without unconserved sides chains): PDB file : Tito_1DLI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DLI-query.scw PDB file : Tito_Scwrl_1DLI.pdb: