Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIHKKFLLVESVLDSYMNVSTLEKVLETARHHLNVPSLLL 1JW2 Chain:A ((16-36)) -------------RRCQTIDTLERVIEKNKYELS------

General information: TITO was launched using: RESULT: Template: 1JW2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 16 -1710 -106.88 -81.43 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : -106.88 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.783

(partial model without unconserved sides chains): PDB file : Tito_1JW2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JW2-query.scw PDB file : Tito_Scwrl_1JW2.pdb: