Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHEPADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLEDSVLIGPRVNLITVNHLTDPKER-RGLS-VKPIHIKKNAWIGAGATILPGVTIGENAIVAANATVTKDVPDNTIVAGIPAKIVKPVERII 5V0Z Chain:A ((20-188)) ----FDQYLINERARAKDICFELNHT------RPSAT---------NKRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKID---

General information: TITO was launched using: RESULT: Template: 5V0Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 843 -67781 -80.40 -405.87 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -80.40 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.604

(partial model without unconserved sides chains): PDB file : Tito_5V0Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5V0Z-query.scw PDB file : Tito_Scwrl_5V0Z.pdb: