Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence NEDCIVSLVPDGGSFARKTLRSSPGQQHDLQWGKYAFTIRVENG--CAGKKTAGTIPPAHFVSVGRAASLKPTSILRDGDPRPPTAVYPPRQPPRTEGRRTRYGSSGGAVTVGAR 1L5P Chain:A ((1-93)) --GTITAVK--GGV--KKQLKFEDDQT--------LFTVLTEAGLMSADDTCQGNKACGKCICKHVSGKVAAA----EDDEKEFLEDQPANA--RLACAITLSGENDGAVFEL--

General information: TITO was launched using: RESULT: Template: 1L5P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 424 -6309 -14.88 -69.32 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -14.88 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.295

(partial model without unconserved sides chains): PDB file : Tito_1L5P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L5P-query.scw PDB file : Tito_Scwrl_1L5P.pdb: