Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG 1EXQ Chain:A ((3-147)) PGIWQLDCTHL------EGKVILVAVHVASGYIEAEVIPA-ETGQETAYFLLKLAGRW-PV-KTIHTDNGSNFTGATVRAACDWAGIKQEDGIPY-------VESMNKELKKIIGQV----RDQAEHLKTAVQMAVFIHNK-KRKGGIGGYSAGERIVD---

General information: TITO was launched using: RESULT: Template: 1EXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 607 -60427 -99.55 -437.87 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -99.55 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.251

(partial model without unconserved sides chains): PDB file : Tito_1EXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EXQ-query.scw PDB file : Tito_Scwrl_1EXQ.pdb: