Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMRIGLFLLTNLAVLVVAGIILSLFGVGSYHGAGGLNLGNLLVICFVFGMVGSLVSLFMSKWMAKKTTGTELIDPNAPRNQAESWLLQTVAELSQRAGINMPEVGIFPS----YQSNAFATGWNKNDALVAVSSGLLERMNKDELRAVLAHEIGHVANGDMVTLALIQGVVNAFVMFFARVVGD---FIDRNVFGRQ---DN-EA-------PGMGYFIITMVLDIVFGILASAIVMWFSRYREYRADEAGARLAGKQAMISALLRLQAETELPDQMPKEMKAFAIAEGKEQGFSLAALFQTHPTIEQRVAALHQLDCP 4IL3 Chain:B ((232-446)) -------------------------------------------------------------------------------------LKKSIESLADRVGFPLDKIFVIDGSKRSSHSNAYFTGLPFTSKRIVLFDTLVNSNSTDEITAVLAHEIGHWQKNHIVNMVIFSQLHTFLIFSLFTSIYRNSSFYNTFGFFVEKSSSGFVDPVITKEFPIIIGFMLFNDLLTPLECAMQFIMSLISRTHEYQADAYAKKLGYKQNLCRALIDLQIKNLS-TMNVDPL--------------YSSYHYSHPTLAERLTALDY----

General information: TITO was launched using: RESULT: Template: 4IL3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 613 -49348 -80.50 -250.49 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.62 3D Compatibility (PKB) : -80.50 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.379

(partial model without unconserved sides chains): PDB file : Tito_4IL3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IL3-query.scw PDB file : Tito_Scwrl_4IL3.pdb: