Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MASLRSSAIPVSDPASGLRITEIFY-SLQGEANASGLPTVFIRLTGCPLRCSYCDTTYSFE-----GGERLSLEHIIETAEK---YQTPYICVTGGEPLAQPNCLILLQRLCDAGFDVSLETSGALDVSRVDPRVSKVLDLKTPTSGEE--HRNLISNLDHLTPR-----DQIKFVICNREDYEWSKQQVEQYQLQTKVSTVWFSPAFAVEKG-----AV-GLPRLARDMAQ-WILDD-KLPVRFQLQLHKLLWNDESGR 5TH5 Chain:B ((23-263)) ---------------KGIPVLEIFGPTIQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGSAKKDIRWMTAEEIFAELKDIGGDAFSHVTISGGNPALLKQLDAFIELLKENNIRAALETQGTVYQDWFTLIDDLTISPKPPSSKMVTNFQKLDHILTSLQENDRQHAVSLKVVIFNDEDLEFAKTVHKRYP----GIPFYLQVGNDDVHTTDDQSLIAHLLGKYEALVDKVAVDAELNLVRVLPQLHTLLWGNKRGV

General information: TITO was launched using: RESULT: Template: 5TH5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1018 5673 5.57 26.14 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : 5.57 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.339

(partial model without unconserved sides chains): PDB file : Tito_5TH5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5TH5-query.scw PDB file : Tito_Scwrl_5TH5.pdb: