Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEKLQKVLARIGLGSRRYMEEVIAAGRVSVNGRVAQVGERIEPGDELRIDGRKVQFQIEDEIRRRVLIYYKPEGEICSRNDPEKRPTVFDHLPQIANDRWVMVGRLDINSTGLLLFTNDGELANRLMHPSNEIEREYAVRVMGEVTPQLRQNMVNGVELEDGPA---KFES-------------FSEIGGEGINRWYQVVVKEGRNREVRRIFESQGLKVSRLLRTRYG--TVILPRELRTGRWMELDKTDIDNLAKSVELKPRQGTGLFGMAKRRTERMTEKPMAARRGGYLRQQRRDDEKEAPANTGNQRKSTGFNRGFKKF 2OML Chain:A ((8-189)) ----------------------------------------------------------NQP---TRVILFNKPYDVLPQFTDEAGRKTLKEFIP---VQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIR-R-KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTL--RLIRYAMGDYSLD-NLANGEWREVTD---------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2OML.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 735 -19592 -26.66 -120.19 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -26.66 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.520

(partial model without unconserved sides chains): PDB file : Tito_2OML.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OML-query.scw PDB file : Tito_Scwrl_2OML.pdb: