Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LCTTIQKGQIFRNILTCMSEFYIKEEFSYTVCNGKNYASPNRTILCIWEGHIIHVRLDERCNWTRLEGDQTEELESQNVEFKVLQKCVASKYKLDPP----HAWDA-GHGVKLG- 3G12 Chain:A ((4-119)) -SLLITSITINTSHLQGMLGFYRIIGFQFTASSEVHRAVHNGVEFSLYSIQ----NPQRSQIPSLQLGFQITDLEKTVQELVKIPGAMCILDPTDMPGKKAIVLDPDGHSIELCE

General information: TITO was launched using: RESULT: Template: 3G12.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 385 -28972 -75.25 -278.57 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -75.25 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.079

(partial model without unconserved sides chains): PDB file : Tito_3G12.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G12-query.scw PDB file : Tito_Scwrl_3G12.pdb: