Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDRVKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVAAERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF 1IV0 Chain:A ((1-98)) MRVGALDVGEARIGLAVGEEGVPLASGRGYLVRKT--LEEDVEALLDFVRREGLGKLVVGLPLRTDLKESAQAGKVLPLVEALRAR-GVEVELWDERFTTK--------------------------------------

General information: TITO was launched using: RESULT: Template: 1IV0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 349 -43840 -125.62 -447.35 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -125.62 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.514

(partial model without unconserved sides chains): PDB file : Tito_1IV0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IV0-query.scw PDB file : Tito_Scwrl_1IV0.pdb: