Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDEANKQLTDARFKRLV------GVQRTTFEEMLAVLKTAYQLK-------HAKGGRKPKLS-LEDLLMATLQYV------------------------------------------------------------------------------------------------------------------------------------------------- 5DLK Chain:A ((19-476)) EPFSLSPIKDPQALHKELCSKNVIPVTSTLEDLLPATQAQHVFIKRGTFHSYNWTIKGRSLNMDRLRETCQSLVDRHSILRTSFVEHEGHPIQLVLANLDVKVREVQCWPGEDPMEVCKALWDGKDWPTLNVLGGSLPVRFTLVSCPGNEHVVLTIQISHSQWDGVSIPKLFSDFAAIYNQTPLPPTSDFAHYLYHRVSSAREDVQQDPTFQFWRHYLDGAKMAVPFAPGQTLWTFKGIVPPTLPSGITMATLVKAATALFLSYHLGSRDVVFGHTVNGRNLPMDNIESLLGCTLNFVPLRVTFPEDSTDWTVMDLLHHTQTQYTRALSHEHVELRDIFQHSTNWPAETPLSLIVQHQNIDLSFSLPLRGSSLDVQYSKFARFDPLDEVWIFTEPHADRLEVQVCANSRVLGQEQATELANNISAIITKFSTDPTARLLDITF

General information: TITO was launched using: RESULT: Template: 5DLK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 79 1375 17.41 22.18 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : 17.41 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.259

(partial model without unconserved sides chains): PDB file : Tito_5DLK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DLK-query.scw PDB file : Tito_Scwrl_5DLK.pdb: