Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMNMPVQHILQSV-DWSKYSFEEWCRQLGAWLNGDTEIMVKIVKTMPTKRITQKQREK--------LIAMYMSDENL----KDRLCTRRKGTCCQLNDNEARALHRLIIDIKLIEDHI--LQDWISAIWSHHVMGNSLRDIAQSNDTSVNQIRQDLKCGLAYIK---SRNPQFKFETFEKTA---------------------------------- 5C74 Chain:A ((1-211)) --MKYIIEHMEEGFSEWVILEYSQILREVG----AENLILSSLPESTTEKDIPQRLLKLGLRWTTKDLKGINEDFKDLELLKDGRVCLLDPRATIDLQPEDATKFDYFVFGGILGDHPPRDRTKELKTAYPNLLISRRLGDKQMTTDTAIRTTQLIIKDRIAFEDIKFIDYPEFRFNKNEATEMPFRYVLDKEGKPILPEGMLDLIKKDSLEHHHHH

General information: TITO was launched using: RESULT: Template: 5C74.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 696 20041 28.79 126.04 target 2D structure prediction score : 0.35 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 28.79 2D Compatibility (Sec. Struct. Predict.) : 0.35 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.206

(partial model without unconserved sides chains): PDB file : Tito_5C74.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C74-query.scw PDB file : Tito_Scwrl_5C74.pdb: