Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYK---PKTVVVGCDIRLSSEALKQAAIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPMDYNGMKLVRENARPISADTGLKEIQALAETNNFEEVGQKGTTQSYNILPEFVDHLLTYIEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFIKIHHEADGTFPNGIPNPILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQSGEKIVHDPRLVWNTFDIVDEYKGVTVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFRDF-AYCDSGMIPWLLTIVLLSETGQSLSTLVENMIAKFPC-SGEINFKVADTQTTIQKIFDFYADQNPQIDRTDGVSLNFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQYYVDELTGLIQN 1P5D Chain:X ((9-452)) -LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIVVA-GETLANEQ-IQALRERIEKNDLA--SGVGSVEQVDILPRYFKQIRDDIA--MAKPMKVVVDCGNGVAGVIAPQLIEAL---G--CSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQL-----

General information: TITO was launched using: RESULT: Template: 1P5D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 2839 -2073 -0.73 -4.72 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain X : 0.75 3D Compatibility (PKB) : -0.73 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_1P5D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P5D-query.scw PDB file : Tito_Scwrl_1P5D.pdb: