Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------MATPFW-YNTALHLLKPFYRWRIKRRAESLE--------LYQQECLERFGPFEAPKNVKAIWFHAVSVGE------TNAAQPLIEYYLKLGQPVLVTNTTKTGQARAKSLFLKEPYLDLFQAVYLPVDQKPLL-----KKFFELYQPKLLALVETELWPN-------LIDQAKLQHVPCLLLNARLSEKSAKGYGKVSGLTAGMLKQLDWVLAQDSATRQRYVELGLDEHKS-QVVGNIKFDIHAPEAFIKQAAQLRQQWYLENRQVVTIASTHAPEEQQILEAFAPYLN------SDRELVCIVVPRHPERFDEVFEICQNLNL----ITHRRSMGQSIHASTQVYLADSMGELWLWY---------ALSQVCFVGGSLNEPGGGHNILEPMVLNVPTVVGPRYFNFQTIVDEFIDENA---VLIAQDAQQVVDIWLACLAEPEATEQLVAQAHKVLQR---NQGSLQKHIGVINRYLAEKS 4X7P Chain:A ((1-493)) MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTGTYIAYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVDNKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKD-SKDSIMICDGPGSFPKMFNTNHKNAQKYGVIHVNHHENFDDTGAFK---KSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSVKDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYG----PSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYSTESILEKWLNLFNS------

General information: TITO was launched using: RESULT: Template: 4X7P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1935 31693 16.38 76.18 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 16.38 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.174

(partial model without unconserved sides chains): PDB file : Tito_4X7P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4X7P-query.scw PDB file : Tito_Scwrl_4X7P.pdb: