Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKLVVFSGAGMSAESGISTFRDSNGLWENYDIQQVATPEAWERNPALVQRFYNERRKNILEAQPNEAHQYIAKLQDHYDVQ-----VITQNIDDPHERAGSQNVLHLHGNIRLAKS------------------SGPDA-QYTTQFYEVNGWKL-DLEQDFCPNGYPLRPHVVWFGEAV-PA-YEEAIRLVQSADIFIVIGSTLSVYPVAALVHEIPHYSKAYYIAPQADHSRVPPQYKLLNMTATEGMHELFNQLTS 4F56 Chain:B ((24-235)) ---IVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFYHYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGC--GGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQV------------------------------------------

General information: TITO was launched using: RESULT: Template: 4F56.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 838 -4888 -5.83 -26.42 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.74 3D Compatibility (PKB) : -5.83 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.461

(partial model without unconserved sides chains): PDB file : Tito_4F56.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4F56-query.scw PDB file : Tito_Scwrl_4F56.pdb: