Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDSYSPYKGKSGLKRILNATSYSISGFKAAYQNEAAFRQIVLINLVLIPVSFFLDVTRGEHALMIIVCLFAIIVELFNSTIEAVVDRVSLEKHQLSKNAKDMGSAAQFVALSIIVATWLIILFG 5DWK Chain:B ((16-126)) ------------FTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLCVVIAAWLDVDAVTRVLLISSVMLVMIVELLNSAIEAVVDRIG---HELSGRAKDLGSAAVLIAIIDAVITWAILLW-

General information: TITO was launched using: RESULT: Template: 5DWK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 224 -48324 -215.73 -447.44 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : -215.73 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.358

(partial model without unconserved sides chains): PDB file : Tito_5DWK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DWK-query.scw PDB file : Tito_Scwrl_5DWK.pdb: