Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKGIYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADSHLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE 3CXK Chain:A ((32-161)) ---PYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTALFESGAKYHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKP---------------

General information: TITO was launched using: RESULT: Template: 3CXK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 654 -37457 -57.27 -288.13 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -57.27 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.591

(partial model without unconserved sides chains): PDB file : Tito_3CXK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CXK-query.scw PDB file : Tito_Scwrl_3CXK.pdb: