Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLVMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGYTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL 3MMX Chain:G ((4-190)) --------------------------RKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQ-----------SVESRLQMLELATEAEEHFSICLEELS----SYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIEALLDLVTFVGVARPGYKLRTPYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYE---

General information: TITO was launched using: RESULT: Template: 3MMX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 824 -156228 -189.60 -908.30 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain G : 0.80 3D Compatibility (PKB) : -189.60 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.653

(partial model without unconserved sides chains): PDB file : Tito_3MMX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MMX-query.scw PDB file : Tito_Scwrl_3MMX.pdb: