Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MALVKTKLAAAPQPSRTPTPGSSPKEWTPPTHTHESPEHLSTDEPDVLVP----AHKYVYDVKTCAWK----GVDTMLRVL----HPNRGLSQGTMRVCFALEELDE---TGFSSRMVAKMFRHNISKVV-----ESDYFNEGEAQCICGIFAEKFN-------------RVQVPAGFQRHIVS-FLQCETVRIKLSEVPEAYQHKRSGFFSYRTTDS----ADILFTMEPRLAGNFTKYTNNFGDVYDGFERRQSLEEEKKRHRVLMAVEAFSHFTLVES---GGSMLVCDLQGVNDFL--TDPQIHTEDGKGLGMGNMGQDGIRKWMEAHVCNEVCRAIMLEPLSK--------------GLRNFTRTAENESRVSYYQILRA--KLRSQTPVRPEDIIPLSKPLSLMS-DDERLEYAMRL-SALLSE-------- 4XGC Chain:D ((5-457)) DRELVSIRRFLKERLQRDYTTLRGYAKERSNVRLLLQRTAEMGESNSLLLLGPRGSGKTTLINSVLADLLPNKSFGENTLIVHLDGNLHTDDRVALKSITVQMQLENAADGKVFGSFAENLAFLLQCLKSKSVIFILEEFDLFCAHHNQTLLYNLFDVSQSAQAPICVLGVTCRLDVIELLEKRVKSRFSHRQVFLFPSLRRFEDYVDLCRDLLSLPTGNSLLLAAEKIYNLQNIQSGALYFSRNHFDPGEYGFSPRLRDAWNKQICKVLATQQARSTLQALHDFDISEAYLKNFLFRLVAHLRPQSPHITAEKMAAVGSQFEGDDKIELLCGLS-VLELCLIIAIKHHSQIYDRDSFNFEIIYARFSKFAKVSTTMQAVERSIVLKAFEHLRIAELIMPLTKVQKEFEMHKLALTYSQIHHCMQRYQALPTEVAQWAQSS

General information: TITO was launched using: RESULT: Template: 4XGC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1590 12139 7.63 32.99 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain D : 0.63 3D Compatibility (PKB) : 7.63 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.139

(partial model without unconserved sides chains): PDB file : Tito_4XGC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XGC-query.scw PDB file : Tito_Scwrl_4XGC.pdb: