Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQELANRLAIQNFVNAYMQETGKGYLLSFDQQSSTQQAFSSGSTLLTLPLPSIQAECSVPLSYVSRVGRHRLAALPKMCIDGQWQKFSAGTIVSLLLEELVIES-QFKLDAASLLEKWIQSRDALLQFLKQRHNDFDDLVKAGQNFIESEQALILGHSMHPAPKSRNGFVHEDWLKFSPEHAGKTQLHYWLVHQNYIAEGCATEQ--PISDQVKDAIRWCLSESDLNLLKTHVEFKLLPLHPWQARYLQGKPWFEQLKQTGQLIDIGLRGWQFSPTTPIRTLASFNAPWMVKTSLSVMITNSIRVNLAKECHRGEISYRLWHSDLGKKILKQCPTLKAVNDPAWIALQIDG-E-IINETICIFRDQPFA--VQQQVTCIASLCQDHPNKEL-NRFNALFDQIAQKNQQTNFKEIALDWFDHFLKIGLAPLMYVYHKYGMAFESHQQNVLLELEDGFPKNLWLRDNQGFHYIEEFATEIVEALPDLLEKAHAVGPKDFVDERFSYYFFGNTLFGLINAIGATGYISEDELLIHLQQNLLQLLEQYPDSTLLQGLLFNDSLPYKGNLLTRLHELDELIAPLEHQSVYVQLPNPLYVEQKDVSYA 5JM8 Chain:A ((11-574)) ----TLDVAAQCFLNSLVRETKDWRLTEY------------QPTQLIIPLGE-QQALHFRVAYFSPTQHHRFEFPARLVTASGSHPVDFATLSRLIVDKLQHQLLLPATSCETFHQRVMESHAHTQQAIDARHDWAA-LREKALNFGEAEQALLVGHAFHPAPKSHEPFNQQEAERYLPDFAPHFPLRWFAVNKTQIAGESLHLNLQQRLTRFAAE----NAPQ--LLNELSDNQWLFPLHPWQGEYLLQQEWCQELVAKGLIKDLGEAGAPWLPTTSSRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVKRGMRLARLAQTDDWQTLQARFPTFRVMQEDGWAGLRDLHGNIMQESL-FALRENLLVDQPQSQTNVLVSLTQAAPDG-GDSLLVAAVKRLSDR-LGITAQQAAHAWVDAYCHQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGLIYRDCQGSAFMPHAAGWLDTIGE---AQAENVFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAEMRDQVTHKTCLNYVLENPYWNVKGNFFCYLN---------DPSVIYFDFANPLLAQ-------

General information: TITO was launched using: RESULT: Template: 5JM8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3123 -66761 -21.38 -121.83 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -21.38 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_5JM8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JM8-query.scw PDB file : Tito_Scwrl_5JM8.pdb: