Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDSQQSKPKHVMMMAAGTGGHVFPALAVAKQLQQQGCQVSWLATPIGMENRLLKDQNIPIYQIDIQGVRG-NGVIR-----KLAAPFK--ILKATFSAMRYMKQLKVDAVAGFGGYVAGPGGLAARLLGIPVLIHEQNAVAGFT-------------------NAQL--------------SRV-----------------AKVVCEAFPNTFP---ASEKVVTTGNPVRREITDILSPKWRYDEREQAGKPLNILIVGGSLG---AKALNERLPPALKQLQVPLNIFHQCGQQQVEATQALYADAPANLTVQVLPFIEDMAKAYSEADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANAKFLADVGAAKICQQSTMTPEVLNQLFTTLMNRQLL-TEMAVKARQHAQPNATQHVVGLIQKM 1RRV Chain:A ((1-396)) ---------MRVLLSVCGTRGDVEIGVALADRLKALGVQTRMCAPPAA-E-ERLAEVGVPHVPVGLPQHMMLQEGMPPPPPEEEQRLAAMTVEMQFDAVPGAAEGCAAVVAVGDLAAA-TGVRSVAEKLGLPFFYSVPSPVYLASPHLPPAYDEPTTPGVTDIRVLWEERAARFADRYGPTLNRRRAEIGLPPVEDVFGYGHGERPLLAADPVLAPLQPDVDAVQTGAWLLSDERPLP-P-ELEAF--LAAGSPPVHIGFGSSSGRGIADAAKVAVEAIRAQ--GRRVILSRGWTELV--L---PDDRDD--CFAIDEV-NFQALFRRVAAVIHHGSAGTEHVATRAGVPQLVIPRNT----DQPYFAGRVAALGIGVAHDGPTPTFESLSAALTTVLA-PETRARAEAVAGMVLT-DGAAAAADLVL--

General information: TITO was launched using: RESULT: Template: 1RRV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1760 -88903 -50.51 -268.59 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -50.51 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.405

(partial model without unconserved sides chains): PDB file : Tito_1RRV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RRV-query.scw PDB file : Tito_Scwrl_1RRV.pdb: