Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIKLIRADQYTKMLWKNGAGFTLEIARSQGEADFEWRISMAD----VTTSGPFSLFPNKQRIISVLDGQGMVLHVDDLPAKKLKQGDIFAFH------GESQVQSELVDGAIRDLNLIYDPAKFHARFQWLNEAAEQAFISSADLIFIFNQGDE----TEVNVDEHSVQLAAHETLKIEKKSGVTSI--NFPKKQFKCCYIIELIQR--------------- 1QPX Chain:A ((1-215)) ---AVSLDRTRAVFDGSEKSMTLDISNDNKQLPYLAQAWIENENQEKIITGPVIATPPVQRLDPGAKSMVRLSTTPDISKLPQDRESLFYFNLREIPP----------IALCTKIKLFYRPAAIKTRPN-EVWQDQLILNKVSGGYRIENPTPYYVTVIGLGGSEKQAEEGEFETVMLSPRSEQTVKSAN--YNTPYLSYINDYGGRPVLSFICNGSRCSVK

General information: TITO was launched using: RESULT: Template: 1QPX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 764 11411 14.94 65.21 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 14.94 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.215

(partial model without unconserved sides chains): PDB file : Tito_1QPX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QPX-query.scw PDB file : Tito_Scwrl_1QPX.pdb: