Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIRVETQMYKSYLFGSKSLLLISLSMLPMFVSAKTILILGDSISAGYGIDPKQGWVQLLQKRLDQQYPKQHKVVNASVSGETTSGALARLPKLLQ---TYKPEVVVIELGGNDGLRGQPPQMIQQNLSQLIQLSQKQKAKVILFGMKIPPNY--GTAYSKAFENNYKTVSQKYQVKLLPFFLDGVA--GQKQLMQNDLIHPNAQAQSKLLNLAYPYIKGAL 4RW0 Chain:A ((2-184)) --------------------------------NAMEIICFGDSITRGYDVPYGRGWVEICDASIE-----NVNFTNYGEDGCSVQGMIYNIENWAVTAVSDPTRHIFLMCGTNDILQGRDSTYVYKTLVKAIELASTKGMVIIGLETQIDSDMDGLDLVVREVNEQLKAYAAEHNIKVIDFYTTLFEADQIGQIVFAGEVHPNERGYRLMAYKALEVFTR--

General information: TITO was launched using: RESULT: Template: 4RW0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 883 -20034 -22.69 -113.83 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -22.69 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.517

(partial model without unconserved sides chains): PDB file : Tito_4RW0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RW0-query.scw PDB file : Tito_Scwrl_4RW0.pdb: