Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSINYDELMQPVLAFLGCQTPKEWLDEAVNNLDILMQDHANCEKKAAGTAMNLMFRYSFFTDLQVKLAQLVREEMLHYEQVLEFMTKRGQEWKGLSA------GRYAGGLRKEIRTYEPEALIDVLVIGAFVEARSCERFYALAPCV-DDELGRYYRYLLKSESRHFEDYLALALDVAKTAKMKDPEEDIQQRIEHIREVEKNLILTPDDTFRFHSGIPA 3Q4O Chain:A ((23-168)) ---------------------------PISEEEKEGLIEMREEEKLARDVYLTLYNKWK-----LQIFKNIAESEQTHMDAVKYLLEKYNIPDPVKNDSIGVFSNPKFEELYKKLVEKGDKSEVDALKVGATIEDLDIADLEKWINKTDNEDIKFVYENLMKGSRNHMRAFVRMLNNY-------------------------------------------

General information: TITO was launched using: RESULT: Template: 3Q4O.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 594 3386 5.70 24.36 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 5.70 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_3Q4O.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q4O-query.scw PDB file : Tito_Scwrl_3Q4O.pdb: