Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKNCGSGQSKLKALRMHIYFEVDFQEQAQHYQAVLHSRGVTVDLQPIEKLNARFLRLNPDLALCVDENGLWLSANGMKMQPDWKAEIPRLKRASLKSEMIARACQLGEKPVLVDATAGLGHDSLLMAYLGAQIQLVERHPILFTLLEDSKAQAQRDPFLSQFMDRIQLIFADSASYLKQLDQEEKTVDVVYLDPMFPQRDQNQQAIKKQAQVKKQMQLLHLLLPEDGEMDLGGHLLELAKKVAKRVIVKRPRHAIFLANQEPAHQWQGDACRFDAYFQ 2JJQ Chain:A ((290-365)) ------------------------------------------------------------------------------------------------------------EGEKILDMYSGVGTFGIYLAKRGFNVKGFDSNEFAIEMARRNVEINNV---------DAEFEVASDREV------SVKGFDTVIVDPPRAG--------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2JJQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 342 -21670 -63.36 -285.13 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -63.36 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_2JJQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JJQ-query.scw PDB file : Tito_Scwrl_2JJQ.pdb: