Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLYFIIGCCIGS-FLCLTAQRIPLGHSIIYPRSHCVKCCRSLSWYELIPILSIIVQR--FRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLSALLFSLMDLFYFMVHS----HTLFCSWAILWIF--WLQAGVF-----QWQSVLLTFIVGGVCLRYGQSYLGAGDTLLMLSWSGGLSLEE------LLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSSALLIVLHLRY 3BOE Chain:A ((2-210)) ISPAQIAEALQGRGWDAEIVTDASMAGQLVDVRPE--------------GILKCVDGRGSDNTRMGGPKMP----------GGI----YAIAHNRGVTSIEGLKQITKEVASKGHLPSVHGDHSSDMLGCGFFKLWVTGRFDDMGYPRPQFDADQGANAVKDAGGIIEMHHGSH---TEKVVYINLLANKTLEPNENDQRFIVDGWAADKFGLD-VPKFLIAAAATVEMLGGPK---NAKIVVP----

General information: TITO was launched using: RESULT: Template: 3BOE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 976 -101308 -103.80 -536.02 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -103.80 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.261

(partial model without unconserved sides chains): PDB file : Tito_3BOE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BOE-query.scw PDB file : Tito_Scwrl_3BOE.pdb: