Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTPEQLPALSAAGSPSSGGASSHHSPHEASLSFPASVIPGDASAESPRAWSMPRSSTASEESAATSQLQQKPDAPESRLGGRKVVYFVDHSVTSIAYAEGHLMRPSRVRALHALVHSLGLDNAECMTVCHARPATAEEMGAFHRSAYLECLRQAPVICGNPLDEMSLAFQKEFDVPFASQNGDCPLFPEVWALVSSQAGASLACAEALVRGDATVAMNWAGGMHHAAAAHASGFCFVNDIVLCIRRLLRHYQRVLYVDLDVHHGDGVEGAFYGNHRVMTLSLHQFGNGFFPGTGDYPT--RETADSFAINVPLPTRTGDAAYLLSFRTALSSVVQCFDPEAMVVQCGADTIAGDLIGRLCVTTLAHTQCVADVLSLERPTVLLGGGGYHVFHTARCWAIHTATALGR-TAAQLPLYIPRTDPYYMDYRRECTPKRPTLHVFLDPDVDDPLPLGDSLAFWRQLCRSIQWQMRAARLVRQGFFRTLQLCRQRRAALLRQFATQEAGRESGIGVSGPKRPRSANATDRDAKEGVEDRVVSA 4A69 Chain:B ((3-367)) ----------------------------------------------------------------------------------KTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGL--YKKMIVFKPYQASQHDMCRFHSEDYIDFLQRV-----SPTNMQ--GFTKSLNA--FNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELP---------YSEYFEYFAPDF-TLH----PDVSTRIENQNSRQYLDQIRQTIFENLK-------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4A69.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2222 -194407 -87.49 -537.04 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.72 3D Compatibility (PKB) : -87.49 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.520

(partial model without unconserved sides chains): PDB file : Tito_4A69.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4A69-query.scw PDB file : Tito_Scwrl_4A69.pdb: