Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------TQKCIITIRKADPALGQDTL-YDLVSLAPNSDLTFG-KIPASMTEVTFGVDEKCQARLVRGDLSRPYEYKGMQN-PLYGLDGPDFVKKLQA-------W-RRKPENSINFSLW------------------- 3MAH Chain:A ((7-151)) DCIKAVAAKDGITVIKVKS-SNKLLSWHFMRKLFEIFEFYQEPVDMVAT-SEVGVSLTIDNDKNLPDIVRALSDIGDVTVDKDMVIICIVGVGFEARIINALKGVPVRMISYGGSNYNVSVLVKAEDKKKALIALSNKLFN

General information: TITO was launched using: RESULT: Template: 3MAH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 345 -1418 -4.11 -14.18 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -4.11 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.388

(partial model without unconserved sides chains): PDB file : Tito_3MAH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MAH-query.scw PDB file : Tito_Scwrl_3MAH.pdb: