Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence GECHITIWEGKTPIGTEIA-IEGGEYV--TIAGYQCNAGAGCTAHCIGLPKNLKERGVYHGEM----------------------- 4P78 Chain:A ((1-86)) MIYPIFIFKTVEGFDGYFPDIDGCFFAGNTFADISKNAEEAFAVHIEALMNEGFPLPSPPKDPHRYIDDPRLKEEGGILGFVEIDP

General information: TITO was launched using: RESULT: Template: 4P78.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 189 -14082 -74.51 -234.70 target 2D structure prediction score : 0.28 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -74.51 2D Compatibility (Sec. Struct. Predict.) : 0.28 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.173

(partial model without unconserved sides chains): PDB file : Tito_4P78.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P78-query.scw PDB file : Tito_Scwrl_4P78.pdb: