Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIDILTLFPEMFSPL-EHSIVGKAREKGLLDIQYHNFRE-NAEKARHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPR---VILLDPAGKQFDQAYAEDLAQEEELIFICGHYEGYDER-IKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSHQDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLLEHYQLTVEEEKMLAEIKENKE 4YQL Chain:A ((9-249)) MWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLG--------SFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQ----

General information: TITO was launched using: RESULT: Template: 4YQL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 955 35119 36.77 154.71 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : 36.77 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_4YQL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YQL-query.scw PDB file : Tito_Scwrl_4YQL.pdb: