Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDIDAISKALANPLRRQILQWLKEPEHYLPVEECGGSFEKGVCAGHIERLGKVAQSTMSNHLSVLQQAGLIQVQKYGQWSYFSRNEALIQQYIEHLKQTL 3JTH Chain:A ((13-93)) --AVVLLKAMANERRLQILCMLH---------------NQELSVGELCAKLQLSQSALSQHLAWLRRDGLVTTRKEAQTVYYTLKSEEVKAMIKLLHS--

General information: TITO was launched using: RESULT: Template: 3JTH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 275 -48294 -175.61 -596.22 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -175.61 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.606

(partial model without unconserved sides chains): PDB file : Tito_3JTH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JTH-query.scw PDB file : Tito_Scwrl_3JTH.pdb: