Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVNHQIKVLQALASAIAEGGRGVTGTAFPKQPVRALKLYEFEGSPFCRRIREVITLL---NLDGLCCT-------NLLKADFTKSYQIQGTTRV 2X5H Chain:A ((1-92)) GMASLKEIIDELGKQAKEQNKIASRIMKIKGIKR--IVVQLNAVPQDGKIRYSMTIHSQNNFRKQIGITPQDAEDLKLIAEFLEKYSDFLNEYV

General information: TITO was launched using: RESULT: Template: 2X5H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 211 -23836 -112.97 -290.68 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -112.97 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.250

(partial model without unconserved sides chains): PDB file : Tito_2X5H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2X5H-query.scw PDB file : Tito_Scwrl_2X5H.pdb: