Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIQALLLITSAIFISACSPYIVTANPNYSASKSDEKA--EKIKNLFNEAHTTGVLVIQQGQTQQSYGNDLARASTEYVPASTFKMLNALIGLEHHKATTTEVFKWDGQKRLFPEWEKNMTLGDAMKASAIPVYQDLARRIGLELMSNEVKRIGYGNADIGTQVDNFWLVGPLKITPQQEAQFAYKLANKTLPFSQKVQDEVQSMLFIEEKNGNKIYAKSGWGWDVNPQVGWLTGWVVQPQGNIVAFSLNLEMKKGISSSVRKEITYRGLEQLGIL 4Y0U Chain:C ((39-277)) -------------------------------------IIDQNVQALFNEISADAVFVTYDGQNIKKYGTHLDRAKTAYIPASTF-IANALIGLENHKATSTEIFKWDGKPRFFKAWDKDFTLGEAMQASTVPVYQELARRIGPSLMQSELQRIGYGNMQIGTEVDQFWLKGPLTITPIQEVKFVYDLAQGQLPFKPEVQQQVKEMLYVERRGENRLYAKSGWGMAVDPQVGWYVGFVEKADGQVVAFALNMQMKAGDDIALRKQLSLDVLDKLGVF

General information: TITO was launched using: RESULT: Template: 4Y0U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1247 43489 34.87 184.28 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.83 3D Compatibility (PKB) : 34.87 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.634

(partial model without unconserved sides chains): PDB file : Tito_4Y0U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Y0U-query.scw PDB file : Tito_Scwrl_4Y0U.pdb: