Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSFKVALAQFSPHIGNIDSNTQKMIEQANQAKKQDADLIIFPELSVIGYPAEDLLLRPNLNKRMQKAFAQLSEVK------DIVMVFGFVNQTE---------DGQRYNSAAVMKDGQVLGVFNKHNLPNYGVFDEKRYFQKGHQHLVFEYLGHKFGVLICEDIWSINT-VKQLSQLNVDTVLVLNSSPYEVGKPQHRKQTLSELAKQLHLNTVYVNQVGGQDDLIFDGTSFVSNQNGEIALQAPSFKEDLYIAEFDRDTKLYKVV-----------------------------ESAPALETFAEIYQGLVMATRDYVERSGFPGVILGLSGGIDSALTLAIAVDAIGAERVQAVMMPYTYTSQISVEDAAEQARRMGVTFGIAEIHSIVNSFMQTLYPFFGNSPADATEENLQARARGTLLMGLSNKFGNLVLSTGNKSELSVGYCTLYGDMVGGFAVLKDVYKTIVFELAKYRNSLS----ETPVIPERVITRPPSAELRPDQKDQDSLPAYDVLDAILYAYIEEDLGQADIIAKGFDKEVVEKVIRLVDRNEYKRRQGAIGPRITSRAFSRERRYPIVNGWTAND 3N05 Chain:A ((2-583)) SLQLRLALNQIDSTVGDIAGNAEAILRWTRHSAEQGAHLVAFPEMALTGYPVEDLALRSSFVEASRTALRELAARLAEEGFGELPVLVGYLDRSESAQPKYGQPAGAPRNAAAVLHRGRVALTFAKHHLPNYGVFDEFRYFVPGDTMPIVRLHGVDIALAICEDLWQDGGRVPAARSAGAGLLLSVNASPYERDKDDTRLELVRKRAQEAGCTTAYLAMIGGQDELVFDGDSIVVDRDGEVVARAPQFSEGCVVLDLDLPAAEAEPPTGVVDDGLRIDRLVISEEPLPAYEAELAGGYADRLDADEEVYSALVVGLRAYVAKNGFRSVLIGLSGGIDSALVAAIACDALGAQNVYGVSMPSKYSSDHSKGDAAELARRTGLNFRTVSIEPMFDAYMASLG-----L-TGLAEENLQSRLRGTTLMAISNQEGHIVLAPGNKSELAVGYSTLYGDSVGAYGPIKDVYKTSIFRLAEWRNRAAAERGQTPPIPEASITKP----------------DYPVLDAILELYVDRDTGADAIVAAGYDRELVVKTLRMVDTAEYKRRQYPPGTKISAKGFGKDRRLPITNRWRE--

General information: TITO was launched using: RESULT: Template: 3N05.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3016 37304 12.37 72.15 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : 12.37 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_3N05.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3N05-query.scw PDB file : Tito_Scwrl_3N05.pdb: