Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIKSDRWIREMSE-KHGMIEPYAENQVRFDKNGEKLISYGVSSYGYDVRCAREFKVFTNVHSAIVDPKNFDEKSFIDIESDVCIIPPNSFALARTIEYFRIPRNVLTVCLGKSTYARCGIIVN-VTPLEPEWEGHVTLEFSNTTNLPARIYAGEGVAQMLFFESDEVCETSYKDRGGKYQGQTGVTLPKT 4XJC Chain:C ((1-171)) -MILSGKTISEKLTEKELEITPLTEEQIQP--------------ASVDLRLGPHFVTIDDSKEAVISFERPIRYREWTTSDETIVLPPHTFLLATTMETVKLPNHLTAFVEGRSSVGRLGLFIQNAGWVDPGFNGQITLELFNANRLPIELPIGRRICQLVFAEVTGE-VAPY---QGKYLFQKGATMSE-

General information: TITO was launched using: RESULT: Template: 4XJC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 793 -7464 -9.41 -44.17 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain C : 0.77 3D Compatibility (PKB) : -9.41 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.443

(partial model without unconserved sides chains): PDB file : Tito_4XJC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XJC-query.scw PDB file : Tito_Scwrl_4XJC.pdb: