Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNHQAAGGQLVGNIYFERMFIMFHVFYEFQFVEIVKEFFELPYKSDNSLSFDSAFQNCAK-PEWNKIKNKKRNFTSVAKQEFDFFRITNSPEYVPANNEIFSEVGYIKLLNKFMKYAI----TFDDVTIKKFFQYEEFSRDLISELVNFMMTQSKPYKLTNDAQFVLEKIELITDDNGIFKLGQIGWKSQKRLIPLLKKEKE----TLSPINIASILFELW-----STKKIAPCPLDPTKIKEKEKKKEKVEKQEKDNKHSNLYIEVNLDYPEDVPFPNGNYYTLYIKNKRNSLYYGEWDG-----LKHVAKEKKGIFKKVKGDLYQEIEKIRKNQEISQERNLYIVVNKENISIIH-----SNIEFWSSFEN------KVRSVKSKLSTLAHQNKIIGYEASTLEEQTIFNDFLPSWKW-QLLSPEIDLDRHLFELETE--------- 5C3M Chain:B ((5-438)) LKMATIGG---GSSYTPELVEGLIKRY-----------HELPVGELWLVDIPEGKEKLEIVGALAKRMVEKAGVPIEIHLTLDRRRALEGADFVTTQFRVGGLEARAKDERIPLKYGVIGQETNGPGGLFKGLRTIPVILDIIRDMEE-LCPDAWLINFTNPAGMVTEAVLRYTKQEKVVGLCNVPIGMRMGVAKLLGVDADRVHIDFAGLNHMVFGLHVYLDGVEVTEKVIDLVAHPLGWEPDFLKGLKV-----------------------LPCPYHRYYYQTDKMLAEELEAAKTKGTRAEVVQQLEKELFELYKDPRGGAYYSDAACSLISSIYNDKRDIQPVNTRNNGAIASIPPESAVEVNCVITKDGPKPIAVGDLPVAVRGLVQQIKSFERVAAEAAVTGDYQTALVAMTINPLVPSDTIAKQMLDEMLEAHKEHLPQFF

General information: TITO was launched using: RESULT: Template: 5C3M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2020 48803 24.16 131.54 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : 24.16 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.193

(partial model without unconserved sides chains): PDB file : Tito_5C3M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C3M-query.scw PDB file : Tito_Scwrl_5C3M.pdb: