Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMGSKKQEEIMKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFVWHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHISEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRVKNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNY-GGRIGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYFDPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPF-HPERYY---EVFDLPGKKMNNSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEFIGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKSASWYQTLIDKRELDLPDEIYK 1GON Chain:A ((15-477)) -----------ALTFPEGFLWGSATASYQIEGAAAEDGRTPSIWDTYARTPGR-VRNGDTGDVATDHYHRWREDVALMAELGLGAYRFSLAWPRIQPTGRG-PALQKGLDFYRRLADELLAKGIQPVATLYHWDLPQELENA-GGWPERATAERFAEYAAIAADALGDRVKTWTTLNEPWCSAFLGYGSGVHAPGRTDPVAALRAAHHLNLGHGLAVQALRDRLPADAQCSVTLNIHHVRPLTDSDADADAVRRIDALANRVFTGPMLQGAYPEDLVKDTAGLTDWSFVRDGDLRLAH-QKLDFLGVNYYSPTLV------------SAHSPWPGADRVAFHQPP-GETTAMGWAVDPSGLYELLRRLSSDFPALPLVITENGAAFHDYAD--P-EGNVNDPERIAYVRDHLAAVHRAIKDGSDVRGYFLWSLLDNFEWAHGYSKRFGAVYVDYPT-GTRIPKASARWYAEVARTGVLP-------

General information: TITO was launched using: RESULT: Template: 1GON.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2704 -100535 -37.18 -227.45 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -37.18 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_1GON.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GON-query.scw PDB file : Tito_Scwrl_1GON.pdb: