Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGWIIMKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELGVPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEV-AS-VSIPNLVRIFMEKHPDIQLTIMQHHLPDDIT-----DPVLYITSE-M---KPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSI-ELTISSTTDDPATLRSIVKQGLAVSFFPKVSWSY-DKNDPFVLREIKDLPLTRTIYLSSSFTE-DHPLIKMIAKTMREFYLGK 3FXQ Chain:A ((1-296)) ----MLKLQTLQALICIEEVGSLRAAAQLLHLSQPALSAAIQQLEDELKAPLLVRTKRGVSLTSFGQAFMKHARLIVTESRRAQEEIGQLRGRWEGHITFAASPAIALAALPLALASFAREFPDVTVNVRDGMYPAVSPQLRDGTLDFALTAAHKHDIDTDLEAQPLYVSDVVIVGQRQHPMANA--TRLAELQECRWAFSSAPRGPGAIIRNAFARYGLPEPKLGLVCESFLALPGVVAHSDLLTTMPRTLYERNAFKDQLCSIPLQDALPNPTIYVLRRHDLPVTPAAAGLIRWIQHHAL--

General information: TITO was launched using: RESULT: Template: 3FXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1215 -59331 -48.83 -210.39 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -48.83 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.541

(partial model without unconserved sides chains): PDB file : Tito_3FXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FXQ-query.scw PDB file : Tito_Scwrl_3FXQ.pdb: