Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEELAGEHRLFEKRNCDKTFVTVPSFFCYAILDVKNRRNKMREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATFDNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK 2D9R Chain:A ((20-103)) -------------------------------------------SPIEFDAIIRQVP-DMDAAYVEIPFDVKTVYGKGRVRVNATFDGYPYTGYIVRMG------LPCHILGLRQDIRRAIGKQPGDSVYVTLLP-

General information: TITO was launched using: RESULT: Template: 2D9R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 369 -73813 -200.04 -878.73 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -200.04 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.623

(partial model without unconserved sides chains): PDB file : Tito_2D9R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D9R-query.scw PDB file : Tito_Scwrl_2D9R.pdb: