Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREMPFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRG-LEVYPEGFLEYLQNFEFKATVRSAREGELVFANEPL----------IQVEGPLAHCQLVETALLNMVNFQ--------------TLIATKAARIKSVIGEDPLLEFGTRRAQELDAA----------VWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGN--------DYEAFMAYAKTH-K--DCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVREQLDA-AGFT--EAKIYASNDLDEATILNLKM---QKAKIDVWGVGTKLITAYD--------QPALGAVFKLVSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEEAIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEEYKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA 1VLP Chain:B ((15-420)) ----EPVIKSLLDTDMYKITMHAAVFTNFP-DVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLRFTEEEIEYLKQEIPYLPSAYIKYISS----SNYKLHPEEQISFTSEEIEGKPTHYKLKILVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDN-GIRFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDD-FLKSFRPPYS-----DAYVGVRQDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNG-----NHAIKISDNLGKNM-GDPATVKRV--------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1VLP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1663 18767 11.28 54.24 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : 11.28 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.372

(partial model without unconserved sides chains): PDB file : Tito_1VLP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VLP-query.scw PDB file : Tito_Scwrl_1VLP.pdb: