Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MCCFVVYGGVLNMSDKKTSLVICFTPLQMLIAEK---IVAQQPSVDLIVIALNNNDKYKYYYNIFQHPNIAKQYYLFDNNKSRF--------FKFINIIKFNENFKLEKFYENIYISSIDNKYTHNILSKVNFNN-------LYTYDDGTANIVKNSIYFKQTFESKLKDIVLKLIGIRFNLNKIKKLSRKHYTIYKGIQNIVEQTEYVSIIEKKEEDRNIFIDQEIKIFLGQPLKDIDKNFDTLALKKLLVME---EVNYHFKHPRETDEAFFEEIKTSYIFEDFFAKELS---KYRKVIIYTLSSTAALNIISLDNVEIRLIKNNTVEIKYPDLVQLFIKSGATVIDMDSIK--------------------------------- 4H2Q Chain:A ((10-379)) KTRRAEVAGG--GFAGLTAAIALKQNGWDVRLHEKSSELRAFGAGIYLWHNGLRVLEGLGALDDVLQGSHTPPTYETWMHNKSVSKETFNGLPWRIMTRSHLHDALVNRARALGVDISVNSEAVAADPVGRLTLQTGEVLEADLIVGADGVGSKVRDSIGFKQDRW-VSKDGLIRLIVPRMK----KELGHGEWDNTIDMWNFWPRVQRILYSPCNEN----------ELYLGLMAPAADPRGSSVPIDLEVWVEMFPFLEPCLIEAAKLKTARYDKYETTKL-DSWTRGKVALVGDAAHAMCPALAQGAGCAMVNAFSLSQDLEEGSSVEDALVAWETRIRPITDRCQALSGDYAANRSLSKGNMFTPAALEAARYDPLRRVYSWPQ

General information: TITO was launched using: RESULT: Template: 4H2Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1852 40904 22.09 131.10 target 2D structure prediction score : 0.26 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 22.09 2D Compatibility (Sec. Struct. Predict.) : 0.26 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.089

(partial model without unconserved sides chains): PDB file : Tito_4H2Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H2Q-query.scw PDB file : Tito_Scwrl_4H2Q.pdb: