Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQYQMITREQCLYWDQEDELKKFKDEFALPEGVIYLDGNSLGARPKKSLAVAQHIISQEWGED-LIN-SWNKADWWGLPTRLGDKVAKLVGAEQGEVVISDSTTLNLFKVLSAAVKIQADKFPEHKIIVAEKDAFPTDIYIIEGFIDLIQKGYQVELID--------GVEDLSRALE----KDVAVVVLSHVNYRTGYFYDMASINEQIHSK--------DALVIWDLCHSVGAVPMHLNQTDSDFAIGCTYKYLNGGPGSPALLWVNEKHRD-QFWQPLSGWWSHKKPFDMAQHYEPANSIRRYLCGTQPVISMSLIECGVDIFLHADMQKIREKSLKLTDLFIQLVHQECSEFGFELITPLDHKHRGSHVSYRHEF--GYEIIQALIARGVIGDYR---EPAVLRFGITPLYLGFEDIWNAVQHLKATMLNSEWKNKEYLVRGEVT 5I90 Chain:B ((38-426)) -----------------NKWKALRQQFDLDPQYLHFANFLLTSHPRPVREAIE-RLRVRFDRNPGEAVDWHREEIWKYEDEARAWAGRYFAVQPGQVALTGSTTDGLAAIYGGLLVQ------PGKEILTSSHEHYSTYTTLEYRHKRMGT--QVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGVHGFGVEDVSFADFDCDYFIAGTHKWLFGPRGT-GVIIARSEQLQEHLVPSIPTFSR-ADNFG----------TLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNAYLKQRLGEH---PKVRLVTPTSPELSSGFTFFRVEGRDCEAVAKHLMAHRVISDAVDRDVGPVVRLAPSL-LNDEAEIDRVLEILAPQL-----------------

General information: TITO was launched using: RESULT: Template: 5I90.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1934 -4471 -2.31 -12.38 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : -2.31 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_5I90.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5I90-query.scw PDB file : Tito_Scwrl_5I90.pdb: