Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHIVIPARFSSSRLPGKPLLLIHDRPMILRVVDQAKKVEGFDDLCVATDDERIAEICRAEGVDVVLTSADHPSGTDRLSEVARIKGWDAD-DIIVNVQGDEPLLPAQLVQQVAKLLVDKPNCSMSTLCEPIHALDEFQRDSIVKVVMSKQNEALYFSRATIPYDRDSAKQAEPTLHSQAFRHLGLYAYRVSLLQEYVTWEMGKLEKLESLEQLRVLENGHRIAIAVAEANLPPGVDTQADL----DRLNNMPVESFE 2Y6P Chain:B ((3-234)) -RAVIIPARLGSTRLKEKPLKNLLGKPLIRWVVEGL--VKTGERVILATDSERVKEVV-EDLCEVFLTPSDLPSGSDRVLYVVR----DLDVDLIINYQGDEPFVYEEDIKLIFREL--EKGERVVTLAR--KDKEAYERPEDVKVVLDREGYALYFSRSPIPYFRKND-----TFY--PLKHVGIYGFRKETLMEFGAMPPSKLEQIEGLEQLRLLENGIKIKVLITE-NYYHGVDTEEDLKIVEEKLKNL------

General information: TITO was launched using: RESULT: Template: 2Y6P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1204 -66440 -55.18 -292.69 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -55.18 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.428

(partial model without unconserved sides chains): PDB file : Tito_2Y6P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y6P-query.scw PDB file : Tito_Scwrl_2Y6P.pdb: